本片基于真实历史故事改编。1942年1月，日本战争机器的铁蹄席卷东南亚。在这里，有一个叫做新不列颠的岛屿上，有一座天主教传教站，这里的澳大利亚护士们克服种种困难的条件，悉心照顾手上的澳大利亚士兵。(文/life_is_good@YDY)
January,1942.TheJapanesewarmachinethundersacrossSouthEastAsia.Initspath,ontheislandofNewBritain,liesatinyCatholicmissionstation,Vunapope.HereahandfulofAustraliannursestakerefugewithwoundedAustraliansoldiers.
SistersofWarisinspiredbythetruestoryoftwoextraordinaryAustralianwomen,LornaWhyte,(nowLornaJohnston)anarmynurseandSisterBereniceTwohill,aCatholicnunfromcountryNewSouthWaleswhowasstationedatVunapope.Althoughtheyweretwoverydifferentwomen,theirfriendshipwouldsurvivetheperilouseventsthatfollowed.SistersofWarisadaptedfromwartimediariesandinterviewswithLorna,SisterBereniceandotherswhowitnessedtheseevents.Thestoryoftheircaptivity,theirextraordinarycourageandtheirwilltoprevailhasneverbeentold.