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Despitequalifyingforarmedforce,Karthik('Jayam'Ravi)preferstobeatrafficcopinOotyashebelievesthatsuchanoriskyjobwouldhelphimgetenoughtimetolookafterhiscutelittlesisterVidhya(BabyAnikha).KarthikalsohasashortlivedonesidelovestorywithRenu(LakshmiMenon),whoisadoctor.Whenahazardouschemicalinthenearbyindustrygetsleaked,adogconsumesitandturnsintoazombie.Asthedogbitesawatchman,hetoobecomesazombieandeventually,thevirusspreadsrapidlyacrossthetown.CanKarthiksavehissisterandthecity?